In a separate mixing bowl, whisk together the whole milk, evaporated milk, salt, black pepper, paprika, garlic powder, and onion powder.
Pour the milk mixture over the macaroni and cheese layers in the slow cooker.
Cover the slow cooker and cook on low for 3-4 hours, or until the mac and cheese is hot and bubbly, and the cheese is fully melted.
Stir the mac and cheese well before serving to ensure a creamy consistency.
You can add extra shredded cheese on top and let it melt for a cheesy crust during the last 15-30 minutes of cooking if desired.
Nutrition (per serving, based on 8 servings):
Nutritional values are approximate and may vary depending on serving size and ingredients used